Prevention of CV Disease

Evolution Of Cardiovascular Risk Prediction Algorithms

2005
FRAMINGHAM Chart
Risk prediction algorithms have evolved since Framingham to account for key risk factors and social determinants of health.

Advancement Of High-Throughput Sequencing (Hts)

1977
Blood Presure Cuff
Revolutionary publications pave the way for polygenic risk scores and targeted therapy developments like PCSK9i and APOCIII.

Development Of High Blood Pressure Standards & Treatments

Timeline Graphic
  • 1959
    Build and Blood Pressure Studies demonstrated increase in mortality associated with incremental increase in systolic and diastolic blood pressures.
    BP Graphic
  • 1967
    Veterans Administration Cooperative Studies show evidence for the beneficial impact of lowering blood pressure with antihypertensive agents.
  • 1970s
    NHLBI Hypertension Task Force formed to improve blood pressure control and treatment in the US.
    NHLBI Photos
  • 2001
    Framingham Heart Study observes increments in systolic or diastolic blood pressure associated with increases in mortality.